Heart failure among meat eaters through changes in gut bacteria confirmed in 2014

Here is another study backing up the ground-breaking research from 2013 on how meat changes your gut bacteria into TMAO. 

The study has confirmed again that TMAO travels to the bloodstream and clogs arteries, leading to heart failure or cardiovascular disease. 

“TMAO testing may help to tailor dietary efforts to the individual in the hopes of reducing future risks among those high-risk subjects”
Dr. W.H. Wilson Tang, of the Department of Cardiovascular Medicine at the Miller Family Heart and Vascular Institute, October 2014. 

“A diet high in carnitine shifts our gut ‘biology’ so meat eaters actually generate more TMAO and compound their risk of cardiovascular disease”
Cleveland Clinic Website, October 2014. 

What do we know already about TMAO?

  • TMAO is produced when gut bacteria digest the amino acid carnitine
  • Carnitine is found in animal foods like beef, fish, chicken, milk and cheese
  • Your body also produces carnitine and stores it in almost every cell in the body for usage when required 

What did the new research find?

  • Lower mortality rates in those with low gut levels of TMAO
  • Those with high levels of TMAO increased their risk of death by 50%
  • High levels of TMAO in the blood tripled the risk of heart failure 

Study by W.H. Wilson Tang, M.D., Department of Cardiovascular Medicine in the Miller Family Heart and Vascular Institute and Lerner Research Institute and Stanley Hazen, M.D., Ph.D., Chair of the Department of Cellular and Molecular Medicine for the Lerner Research Institute and section head of Preventive Cardiology & Rehabilitation in the Miller Family Heart and Vascular Institute at Cleveland Clinic, “Prognostic value of elevated levels of intestinal microbe-generated metabolite trimethylamine-n-oxide in patients with heart failure: Refining the gut hypothesis” as published in the Journal of the American College of Cardiology 2014; 64:1 908–914. Also; study by Cannon JA, McMurray JJV “Gut feelings about heart failure” as published in the Journal of the American College of Cardiology 2014; 64(18): 1915-1916.

Posted: Saturday 29 November 2014