Fasting and calorie restriction continue to support healthy longevity

I have practiced this for over 25 years and detailed my experiences, good and bad, in my book Eat Less, Live Long.  The science and proof just keeps on coming! 

This new research points to another mechanism in the “eat less, live long” process.

“This finding suggests that H2S is one of the key molecules responsible for the benefits of dietary restriction in mammals and lower organisms as well. While more experiments are required to understand how H2S exerts its beneficial effects, it does give us a new perspective on which molecular players to target therapeutically in our efforts to combat human disease and aging”
James Mitchell, associate professor of genetics and complex diseases, Harvard T.H. Chan School of Public Health, December 2014.

These researchers have found that when you fast (particularly for three days or more on fresh vegetable juice or water), or ‘eat less’ generally, you restrict two amino acids (methionine and cysteine), which results in the body changing production amounts of hydrogen sulfide (H2S).

This protects the body during ‘lower than normal’ blood flow. 

High amounts of H2S, are dangerous.  Low amounts, as created and controlled by the body, when either fasting or calorie controlling, is very beneficial and is linked in many studies with longevity.

“These findings give us a better understanding of how dietary interventions extend lifespan and protect against injury. More immediately, they could have important implications for what to eat and not to eat before a planned acute stress like surgery, when the risk of ischemic injury can be relatively high” 

Christopher Hine, research fellow in the Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health (HSPH), December 2014.

The researchers found that “the protection required increased production of H2S, which occurred upon reduction of dietary intake of methionine and cysteine”.

The bottom line here is exactly as I talk about it in Eat Less, Live Long; Eat less, practice Regular Intelligent Fasting® (RIF), and eat better quality foods, if you want a long healthy life free of drugs and disease.

Study by James Mitchell, associate professor of genetics and complex diseases at Harvard T.H. Chan School of Public Health (HSPH), as published in Cell on December 23, 2014.


Posted: Sunday 31 May 2015