Alcohol intake again directly related to breast cancer says latest 2014 scientific review

Alcohol intake again directly related to breast cancer says latest 2014 scientific review

Let’s take a week or so to look at alcohol and whether the science says it really is good for you or not shall we..?

The International Agency for Research on Cancer (2009-2013), finds again, the link between alcohol and breast cancer is strong and robust.

“You cannot get a cancer cell occurring unless DNA is altered.  When you drink, the acetaldehyde is corrupting the DNA of life and puts you on the road to cancer.  One of most common genetic defects in man is our inability to counteract the toxicity of alcohol”
Dr Nick Sheron, the liver unit, Southampton General Hospital.

As published in the American Journal of Preventive Medicine 2014, this research “statistically analyzed” a number of different cohort studies.

As I have spoken about for many years, the main problem with alcohol and human DNA is “ethanol oxidation”, giving us the toxic metabolite byproduct; acetaldehyde.

Alcohol (all alcohol), delivers ethanol, acetaldehyde, free radicals and peroxides to the breast tissues via the bloodstream.

This study again, confirms this to be the case.

In conclusion, the authors wrote: Recent publications add to the current body of evidence that consumption of alcoholic beverages is causally associated to cancer of the female breast, even at low levels of alcohol consumption.  Current data indicate that breast cancer risk does not vary by beverage type and strengthen the evidence that ethanol is the main causal factor; nevertheless, other compounds present in various alcoholic beverages may play a role in, or prevent, the development of breast cancer.  Experimental and epidemiologic studies show that alcohol-induced breast cancer may be stronger for exposure during adolescence and early adulthood.  In addition, there is growing evidence of an environmental impact on the breast cancer epigenome through nutrition”

Studies referenced: WHO. Global health risks: mortality and burden of disease attributable to selected major risks, 2009; And WHO. International Agency for research in Cancer. IARC monograph on the evaluation of carcinogenic risks to humans; And Secretan B, Straif K, Baan R, et al. A review of human carcinogens––Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish. Lancet Oncol. 2009;10(11):1033–1034; And Cogliano VJ, Baan R, Straif K, et al. Preventable exposures associated with human cancers. J Natl Cancer Inst.2011;103(24):1827–1839; And Bloomfield K, Grittner U, Kramer S, Gmel G. Social inequalities in alcohol consumption and alcohol-related problems in the study countries of the EU concerted action “Gender, Culture and Alcohol Problems: a Multi-national Study.” Alcohol Suppl. 2006;41(1):i26–i36; And Schutze M, Boeing H, Pischon T, et al. Alcohol attributable burden of incidence of cancer in eight European countries based on results from prospective cohort study. BMJ. 2011;342:d1584.  This research was supported by the Health General directorate of the French Ministry of Health.


 

Posted: Thursday 17 April 2014