Fatty liver increases risk for liver cancer

Fatty liver increases risk for liver cancer

The more obese and overweight people, the more fatty liver disease, the more liver cancer.  This has been confirmed again in a large analysis with non-alcoholic fatty liver disease and liver cancer both on the rise.

Dr Rubayat Rahman of the University of Missouri in Columbia found on analysis of the Surveillance, Epidemiology, and End Results (SEER) and Medicare databases from 1993 through 2007, that non-alcoholic fatty liver disease (NAFLD) raises your risk of hepatocellular carcinoma (HCC cancer), regardless of other factors.  NAFLD was the third most common risk factor, after infections and alcohol-related diseases. 

The obvious news is that as obesity grows, therefore fatty liver disease grows, therefore cancer grows. 

This analysis confirms that the rate of NAFLD-associated cancer without cirrhosis is growing faster than the rate of disease linked to cirrhosis. 

“The findings are a little scary as this is the most common liver disease and it is strongly associated with obesity and as the obesity epidemic grows, we’re probably not only going to get more cirrhosis and more liver disease, we’re probably going to get more liver cancer”
American Association for the Study of Liver Diseases (AASLD) President Guadalupe Garcia-Tsao, MD, of Yale University School of Medicine. 

Study by Rahman RN, Ibdah JA “Nonalcoholic fatty liver disease without cirrhosis is an emergent and independent risk factor of hepatocellular carcinoma: A population based study” as presented to the 2012 annual meeting of the American Association for the Study of Liver Diseases (AASLD) 2012; Abstract 97.  As reported by MedPage Today on November 13, 2012.

Posted: Wednesday 12 December 2012